Multifaceted Aspects of Metabolic Plasticity in Human Cholangiocarcinoma: An Overview of Current Perspectives

Multifaceted Aspects of Metabolic Plasticity in Human Cholangiocarcinoma: An Overview of Current Perspectives

Cholangiocarcinoma (CCA) is a deadly tumor without an effective therapy. Unique metabolic and bioenergetics features are important hallmarks of tumor cells. Metabolic plasticity allows cancer cells to survive in poor nutrient environments and maximize cell growth by sustaining survival, proliferatio...

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Bibliographic Details
Main Authors: Mirella Pastore, Giulia Lori, Alessandra Gentilini, Maria Letizia Taddei, Giovanni Di Maira, Claudia Campani, Stefania Recalcati, Pietro Invernizzi, Fabio Marra, Chiara Raggi
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
cholangiocarcinoma
mitochondria
oxphos
pgc-1α
tricarboxylic acid cycle
fatty acids
fatty acid synthase
Online Access:https://www.mdpi.com/2073-4409/9/3/596

Internet

https://www.mdpi.com/2073-4409/9/3/596

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