Bacteriophage therapy for the treatment of Mycobacterium tuberculosis infections in humanized mice

Abstract The continuing emergence of new strains of antibiotic-resistant bacteria has renewed interest in phage therapy; however, there has been limited progress in applying phage therapy to multi-drug resistant Mycobacterium tuberculosis (Mtb) infections. In this study, we show that bacteriophage s...

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Bibliographic Details
Main Authors: Fan Yang, Alireza Labani-Motlagh, Jose Alejandro Bohorquez, Josimar Dornelas Moreira, Danish Ansari, Sahil Patel, Fabrizio Spagnolo, Jon Florence, Abhinav Vankayalapati, Tsuyoshi Sakai, Osamu Sato, Mitsuo Ikebe, Ramakrishna Vankayalapati, John J. Dennehy, Buka Samten, Guohua Yi
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-06006-x