MCPerm: a Monte Carlo permutation method for accurately correcting the multiple testing in a meta-analysis of genetic association studies.

MCPerm: a Monte Carlo permutation method for accurately correcting the multiple testing in a meta-analysis of genetic association studies.

Traditional permutation (TradPerm) tests are usually considered the gold standard for multiple testing corrections. However, they can be difficult to complete for the meta-analyses of genetic association studies based on multiple single nucleotide polymorphism loci as they depend on individual-level...

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Bibliographic Details
Main Authors: Yongshuai Jiang, Lanying Zhang, Fanwu Kong, Mingming Zhang, Hongchao Lv, Guiyou Liu, Mingzhi Liao, Rennan Feng, Jin Li, Ruijie Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3931718?pdf=render

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http://europepmc.org/articles/PMC3931718?pdf=render

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