Higher Fibroblast Growth Factor 23 Levels Are Causally Associated With Lower Bone Mineral Density of Heel and Femoral Neck: Evidence From Two-Sample Mendelian Randomization Analysis

Higher Fibroblast Growth Factor 23 Levels Are Causally Associated With Lower Bone Mineral Density of Heel and Femoral Neck: Evidence From Two-Sample Mendelian Randomization Analysis

Background: Previous observational studies have indicated that high levels of fibroblast growth factor 23 (FGF23), a phosphoric hormone that inhibits calcitriol synthesis, in the blood is associated with the reduced bone mineral density (BMD); however, whether this association is causal remains uncl...

Full description

Bibliographic Details
Main Authors: Yue Wang, Hui Wang, Peizhan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Public Health
Subjects:
fibroblast growth factor 23 (FGF23)
single nucleotide polymorphisms (SNPs)
heel
femoral neck
bone mineral density
mendelian randomization
Online Access:https://www.frontiersin.org/article/10.3389/fpubh.2020.00467/full

Internet

https://www.frontiersin.org/article/10.3389/fpubh.2020.00467/full

Similar Items