Comparative analysis of signature genes in PRRSV-infected porcine monocyte-derived cells to different stimuli.

Monocyte-derived DCs (mDCs) are major target cells in porcine reproductive and respiratory syndrome virus (PRRSV) pathogenesis; however, the plasticity of mDCs in response to activation stimuli and PRRSV infection remains unstudied. In this study, we polarized mDCs, and applied genome-wide transcrip...

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Bibliographic Details
Main Authors: Laura C Miller, Damarius S Fleming, Xiangdong Li, Darrell O Bayles, Frank Blecha, Yongming Sang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5519058?pdf=render