HVEM/HIF-1α promoted proliferation and inhibited apoptosis of ovarian cancer cells under hypoxic microenvironment conditions

HVEM/HIF-1α promoted proliferation and inhibited apoptosis of ovarian cancer cells under hypoxic microenvironment conditions

Abstract Background Our previous studies showed the expression of herpes virus entry mediator (HVEM) is high in ovarian cancer samples and correlated to the patient clinic pathological features. As we all know, the hypoxic environment is the main feature of tumor. In this work, we explored the role...

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Bibliographic Details
Main Authors: Liyan Duan, Jie Tao, Xiaoqian Yang, Lei Ye, Yueqian Wu, Qizhi He, Yingchun Duan, Li Chen, Jianlong Zhu
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Ovarian Research
Subjects:
HVEM
Ovarian cancer
HIF-1α
Hypoxic microenvironment
Online Access:http://link.springer.com/article/10.1186/s13048-020-00646-3

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http://link.springer.com/article/10.1186/s13048-020-00646-3

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