Conserved long-range base pairings are associated with pre-mRNA processing of human genes

Functional RNA secondary structure is important for the pre-mRNA processing including splicing, cleavage and polyadenylation, and RNA editing. Here the authors present a catalog of conserved long-range RNA structures in the human transcriptome by defining pairs of conserved complementary regions (PC...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Svetlana Kalmykova, Marina Kalinina, Stepan Denisov, Alexey Mironov, Dmitry Skvortsov, Roderic Guigó, Dmitri Pervouchine
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Nature Portfolio 2021-04-01
Cyfres:Nature Communications
Mynediad Ar-lein:https://doi.org/10.1038/s41467-021-22549-7