Characterizing the emergence and persistence of drug resistant mutations in HIV-1 subtype C infections using 454 ultra deep pyrosequencing

Characterizing the emergence and persistence of drug resistant mutations in HIV-1 subtype C infections using 454 ultra deep pyrosequencing

<p>Abstract</p> <p>Background</p> <p>The role of HIV-1 RNA in the emergence of resistance to antiretroviral therapies (ARTs) is well documented while less is known about the role of historical viruses stored in the proviral DNA. The primary focus of this work was to cha...

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Bibliographic Details
Main Authors: Bansode Vijay, McCormack Grace P, Crampin Amelia C, Ngwira Bagrey, Shrestha Ram K, French Neil, Glynn Judith R, Travers Simon A
Format: Article
Language:English
Published: BMC 2013-01-01
Series:BMC Infectious Diseases
Subjects:
HIV-1
Drug resistance
Subtype C
Malawi
Ultradeep sequencing
Proviral DNA
Online Access:http://www.biomedcentral.com/1471-2334/13/52

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http://www.biomedcentral.com/1471-2334/13/52

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