Cullin-associated and neddylation-dissociated protein 1 (CAND1) alleviates NAFLD by reducing ubiquitinated degradation of ACAA2

Abstract Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder with high morbidity and mortality. The current study aims to explore the role of Cullin-associated and neddylation-dissociated protein 1 (CAND1) in the development of NAFLD and the underlying mechanisms. CAND1 is red...

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Bibliographic Details
Main Authors: Xiang Huang, Xin Liu, Xingda Li, Yang Zhang, Jianjun Gao, Ying Yang, Yuan Jiang, Haiyu Gao, Chongsong Sun, Lina Xuan, Lexin Zhao, Jiahui Song, Hairong Bao, Zhiwen Zhou, Shangxuan Li, Xiaofang Zhang, Yanjie Lu, Xiangyu Zhong, Baofeng Yang, Zhenwei Pan
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40327-5