Double-stranded RNA-dependent protein kinase regulates the motility of breast cancer cells.

Double-stranded RNA-dependent protein kinase regulates the motility of breast cancer cells.

Double-stranded RNA (dsRNA)-dependent protein kinase (PKR) is an interferon-induced protein kinase that plays a central role in the anti-viral process. Due to its pro-apoptotic and anti-proliferative action, there is an increased interest in PKR modulation as an anti-tumor strategy. PKR is overexpre...

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Bibliographic Details
Main Authors: Mei Xu, Gang Chen, Siying Wang, Mingjun Liao, Jacqueline A Frank, Kimberly A Bower, Zhuo Zhang, Xianglin Shi, Jia Luo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3480402?pdf=render

Internet

http://europepmc.org/articles/PMC3480402?pdf=render

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