Arabidopsis thaliana WAPL is essential for the prophase removal of cohesin during meiosis.

Sister chromatid cohesion, which is mediated by the cohesin complex, is essential for the proper segregation of chromosomes in mitosis and meiosis. The establishment of stable sister chromatid cohesion occurs during DNA replication and involves acetylation of the complex by the acetyltransferase CTF...

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Bibliographic Details
Main Authors: Kuntal De, Lauren Sterle, Laura Krueger, Xiaohui Yang, Christopher A Makaroff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4102442?pdf=render