Mutations and Protein Interaction Landscape Reveal Key Cellular Events Perturbed in Upper Motor Neurons with HSP and PLS

Hereditary spastic paraplegia (HSP) and primary lateral sclerosis (PLS) are rare motor neuron diseases, which affect mostly the upper motor neurons (UMNs) in patients. The UMNs display early vulnerability and progressive degeneration, while other cortical neurons mostly remain functional. Identifica...

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Detaylı Bibliyografya
Asıl Yazarlar: Oge Gozutok, Benjamin Ryan Helmold, P. Hande Ozdinler
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: MDPI AG 2021-04-01
Seri Bilgileri:Brain Sciences
Konular:
Online Erişim:https://www.mdpi.com/2076-3425/11/5/578