Functional Significance of Conserved Cysteines in the Extracellular Loops of the ATP Binding Cassette Transporter Pdr11p

Functional Significance of Conserved Cysteines in the Extracellular Loops of the ATP Binding Cassette Transporter Pdr11p

The pleiotropic drug resistance (PDR) transporter Pdr11p is expressed under anaerobic growth conditions at the plasma membrane of the yeast <i>Saccharomyces cerevisiae</i>, where it facilitates the uptake of exogenous sterols. Members of the fungal PDR family contain six conserved cystei...

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Bibliographic Details
Main Authors: Lyubomir Dimitrov Stanchev, Magdalena Marek, Feng Xian, Mara Klöhn, Daniele Silvestro, Gunnar Dittmar, Rosa Laura López-Marqués, Thomas Günther Pomorski
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Journal of Fungi
Subjects:
ABC transport proteins
sterol uptake
disulfide bonds
ATPase activity
protein trafficking
Online Access:https://www.mdpi.com/2309-608X/7/1/2

Internet

https://www.mdpi.com/2309-608X/7/1/2

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