Relationships between Inhibition, Transport and Enhanced Transport via the Organic Cation Transporter 1

Relationships between Inhibition, Transport and Enhanced Transport via the Organic Cation Transporter 1

The organic cation transporter 1 (OCT1, <i>SLC22A1</i>) transports a large number of structurally diverse endogenous and exogenous substrates. There are numerous known competitive and non-competitive inhibitors of OCT1, but there are no studies systematically analyzing the relationship b...

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Bibliographic Details
Main Authors: Ole Jensen, Lukas Gebauer, Jürgen Brockmöller, Christof Dücker
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
OCT1
inhibition
transport
potentiation
enhancement
<i>SLC22A1</i>
Online Access:https://www.mdpi.com/1422-0067/23/4/2007

Internet

https://www.mdpi.com/1422-0067/23/4/2007

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