New approaches for the synthesis, cytotoxicity and toxicity of heterocyclic compounds derived from 2-cyanomethyl benzo[c]imidazole

The reaction of ethyl cyanoacetate 2 with o-phenylenediamine 1 gave the 2-cyanomethylbenzo[c]imidazole 3. The latter compound was used as the key starting material to synthesis biologically active heterocyclic derivatives. Thus, the reaction of compound 3 with cyclohexanone 4 and either of benzaldeh...

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Bibliographic Details
Main Authors: Rafat Mohareb, Abeer Mohamed, Amira Abdalla
Format: Article
Language:English
Published: Slovenian Chemical Society 2016-04-01
Series:Acta Chimica Slovenica
Subjects:
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/1668