Protein Tetratricopeptide Repeat and the Companion Non-tetratricopeptide Repeat Helices: Bioinformatic Analysis of Interhelical Interactions
The tetratricopeptide repeat (TPR) of proteins consists of a 34-amino acid, alpha-helical motif that comprises a pattern of small and large hydrophobic residues, leading to a recognizable signature sequence. Structural and functional studies have documented that tandem TPRs form a superhelix that in...
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2019-09-01
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Series: | Bioinformatics and Biology Insights |
Online Access: | https://doi.org/10.1177/1177932219863363 |