Protein Tetratricopeptide Repeat and the Companion Non-tetratricopeptide Repeat Helices: Bioinformatic Analysis of Interhelical Interactions

The tetratricopeptide repeat (TPR) of proteins consists of a 34-amino acid, alpha-helical motif that comprises a pattern of small and large hydrophobic residues, leading to a recognizable signature sequence. Structural and functional studies have documented that tandem TPRs form a superhelix that in...

Full description

Bibliographic Details
Main Author: Sailen Barik
Format: Article
Language:English
Published: SAGE Publishing 2019-09-01
Series:Bioinformatics and Biology Insights
Online Access:https://doi.org/10.1177/1177932219863363