Clinical experience with a novel assay measuring cytomegalovirus (CMV)-specific CD4+ and CD8+ T-cell immunity by flow cytometry and intracellular cytokine staining to predict clinically significant CMV events

Clinical experience with a novel assay measuring cytomegalovirus (CMV)-specific CD4+ and CD8+ T-cell immunity by flow cytometry and intracellular cytokine staining to predict clinically significant CMV events

Abstract Background Cytomegalovirus (CMV) infection is one of the most common opportunistic infections following organ transplantation, despite administration of CMV prophylaxis. CMV-specific T-cell immunity (TCI) has been associated with reduced rates of CMV infection. We describe for the first tim...

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Bibliographic Details
Main Authors: Ralph Rogers, Kapil Saharia, Aditya Chandorkar, Zoe F. Weiss, Kendra Vieira, Sophia Koo, Dimitrios Farmakiotis
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Infectious Diseases
Subjects:
CMV
Cytomegalovirus
Transplantation
Immunoassays
(val)ganciclovir
Online Access:https://doi.org/10.1186/s12879-020-4787-4

Internet

https://doi.org/10.1186/s12879-020-4787-4

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