Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency

Summary: Mitochondria are composed of many small proteins that control protein synthesis, complex assembly, metabolism, and ion and reactive oxygen species (ROS) handling. We show that a skeletal muscle- and heart-enriched long non-coding RNA, LINC00116, encodes a highly conserved 56-amino-acid micr...

Full description

Bibliographic Details
Main Authors: Colleen S. Stein, Pooja Jadiya, Xiaoming Zhang, Jared M. McLendon, Gabrielle M. Abouassaly, Nathan H. Witmer, Ethan J. Anderson, John W. Elrod, Ryan L. Boudreau
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718308970