Maternal HIV infection drives altered placental Mtb-specific antibody transfer

Maternal HIV infection drives altered placental Mtb-specific antibody transfer

IntroductionPlacental transfer of maternal antibodies is essential for neonatal immunity over the first months of life. In the setting of maternal HIV infection, HIV-exposed uninfected (HEU) infants are at higher risk of developing severe infections, including active tuberculosis (TB). Given our eme...

Full description

Bibliographic Details
Main Authors: Nadege Nziza, Wonyeong Jung, Maanasa Mendu, Tina Chen, Ryan P. McNamara, Sarah M. Fortune, Kees L. M. C. Franken, Tom H. M. Ottenhoff, Bryan Bryson, Joseph Ngonzi, Lisa M. Bebell, Galit Alter
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Microbiology
Subjects:
antibody
placental transfer
neonate
HIV
tuberculosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1171990/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1171990/full

Similar Items