In Vitro Human Monoamine Oxidase Inhibition and Human Dopamine D<sub>4</sub> Receptor Antagonist Effect of Natural Flavonoids for Neuroprotection

In Vitro Human Monoamine Oxidase Inhibition and Human Dopamine D<sub>4</sub> Receptor Antagonist Effect of Natural Flavonoids for Neuroprotection

Natural flavone and isoflavone analogs such as 3′,4′,7-trihydroxyflavone (<b>1</b>), 3′,4′,7-trihydroxyisoflavone (<b>2</b>), and calycosin (<b>3</b>) possess significant neuroprotective activity in Alzheimer’s and Parkinson’s disease. This study highlights the in...

Full description

Bibliographic Details
Main Authors: Pradeep Paudel, Jae Sue Choi, Ritu Prajapati, Su Hui Seong, Se Eun Park, Woo-Chang Kang, Jong-Hoon Ryu, Hyun Ah Jung
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:International Journal of Molecular Sciences
Subjects:
flavonoids
hMAO
GPCRs
dopamine
antagonist
serotonin
Online Access:https://www.mdpi.com/1422-0067/24/21/15859

Internet

https://www.mdpi.com/1422-0067/24/21/15859

Similar Items