Effects of PGK1 on immunoinfiltration by integrated single-cell and bulk RNA-sequencing analysis in sepsis

Effects of PGK1 on immunoinfiltration by integrated single-cell and bulk RNA-sequencing analysis in sepsis

BackgroundSepsis, a life-threatening organ dysfunction caused by a dysregulated immune response to infection, remains a significant global health challenge. Phosphoglycerate kinase 1 (PGK1) has been implicated in regulating inflammation and immune cell infiltration in inflammatory conditions. Howeve...

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Bibliographic Details
Main Authors: Yu Liu, Weijie Li, Lei Lei, Yaoliang Zhou, Mingcheng Huang, Yide Li, Xiaoying Zhang, Yingyu Jiang, Haiqi Wu, Zhihua Zheng, Kongyang Ma, Chun Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
sepsis
PGK1
immune infiltration
single-cell RNA-sequencing
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1449975/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1449975/full

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