Ketone bodies promote stroke recovery via GAT-1-dependent cortical network remodeling

Summary: Stroke is a leading cause of adult disability worldwide, and better drugs are needed to promote functional recovery after stroke. Growing evidence suggests the critical role of network excitability during the repair phase for stroke recovery. Here, we show that β-hydroxybutyrate (β-HB), an...

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Bibliographic Details
Main Authors: Yu-Hui Lin, Di Yang, Huan-Yu Ni, Xiu-Mei Xu, Feng Wu, Long Lin, Jie Chen, Yan-Yu Sun, Zhen-Quan Huang, Shi-Yi Li, Pei-Lin Jiang, Hai-Yin Wu, Lei Chang, Bo Hu, Chun-Xia Luo, Jin Wu, Dong-Ya Zhu
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723003054