A Co-Opted DEAD-Box RNA helicase enhances tombusvirus plus-strand synthesis.

Replication of plus-strand RNA viruses depends on recruited host factors that aid several critical steps during replication. In this paper, we show that an essential translation factor, Ded1p DEAD-box RNA helicase of yeast, directly affects replication of Tomato bushy stunt virus (TBSV). To separate...

Full description

Bibliographic Details
Main Authors: Nikolay Kovalev, Judit Pogany, Peter D Nagy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3280988?pdf=render