Toblerone: detecting exon deletion events in cancer using RNA-seq [version 1; peer review: 2 approved]
Cancer is driven by mutations of the genome that can result in the activation of oncogenes or repression of tumour suppressor genes. In acute lymphoblastic leukemia (ALL) focal deletions in IKAROS family zinc finger 1 (IKZF1) result in the loss of zinc-finger DNA-binding domains and a dominant negat...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2023-02-01
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| Series: | F1000Research |
| Subjects: | |
| Online Access: | https://f1000research.com/articles/12-130/v1 |