Leishmania infantum EndoG is an endo/exo-nuclease essential for parasite survival.

Leishmania infantum EndoG is an endo/exo-nuclease essential for parasite survival.

EndoG, a member of the DNA/RNA non-specific ββα-metal family of nucleases, has been demonstrated to be present in many organisms, including Trypanosomatids. This nuclease participates in the apoptotic program in these parasites by migrating from the mitochondrion to the nucleus, where it takes part...

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Bibliographic Details
Main Authors: Eva Rico, Cristina Oliva, Kilian Jesús Gutierrez, Juan Fernando Alzate, Carlos Mario Genes, David Moreno, Elena Casanova, Alba Gigante, María-Jesús Pérez-Pérez, María-José Camarasa, Joachim Clos, Federico Gago, Antonio Jiménez-Ruiz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3971528?pdf=render

Internet

http://europepmc.org/articles/PMC3971528?pdf=render

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