Transcriptome-wide changes in gene expression, splicing, and lncRNAs in response to a live attenuated dengue virus vaccine

Transcriptome-wide changes in gene expression, splicing, and lncRNAs in response to a live attenuated dengue virus vaccine

Summary: The tetravalent dengue vaccine candidate, TAK-003, induces a functional antibody response, but the titers of antibodies against the four serotypes of the dengue virus (DENV) can vary. Here, through a transcriptomic analysis on whole blood collected from recipients of a two-dose schedule of...

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Bibliographic Details
Main Authors: Eun-Young Kim, Yan Che, Hansi J. Dean, Ramon Lorenzo-Redondo, Michael Stewart, Caroline K. Keller, Daniel Whorf, Dawson Mills, Nikita N. Dulin, Tiffany Kim, Megan Votoupal, Miriam Walter, Ana Fernandez-Sesma, Heejin Kim, Steven M. Wolinsky
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Cell Reports
Subjects:
live attenuated dengue virus vaccine
transcriptome
long noncoding RNA
splicing
gene correlation networks
modular transcriptional repertoire
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722000572

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http://www.sciencedirect.com/science/article/pii/S2211124722000572

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