Transforming Growth Factor Beta 1 869T/C and 915G/C Polymorphisms and Risk of Autism Spectrum Disorders

Background: Transforming growth factor-β1 (TGF-β1) has been found to play a crucial role in early central nervous system development. Several studies have illustrated decreased TGF-β1 levels in sera and brains of autistic children. Two point mutations in the TGF-β1 signal peptide at 869T/C and 915G/...

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Bibliographic Details
Main Authors: Mohammad Reza Khakzad, Farhad Salari, Maryam Javanbakht, Maryam Hojati, Abdolreza Varasteh, Mojtaba Sankian, Mojtaba Meshkat
Format: Article
Language:English
Published: Varastegan Institute for Medical Sciences 2015-05-01
Series:Reports of Biochemistry and Molecular Biology
Subjects:
Online Access:http://rbmb.net/article-1-63-en.pdf