Towards a systematic assessment of assay interference: Identification of extensively tested compounds with high assay promiscuity [version 1; referees: 2 approved]

A large-scale statistical analysis of hit rates of extensively assayed compounds is presented to provide a basis for a further assessment of assay interference potential and multi-target activities. A special feature of this investigation has been the inclusion of compound series information in acti...

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Bibliographic Details
Main Authors: Erik Gilberg, Dagmar Stumpfe, Jürgen Bajorath
Format: Article
Language:English
Published: F1000 Research Ltd 2017-08-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/6-1505/v1