Progesterone prevents HGSOC by promoting precancerous cell pyroptosis via inducing fibroblast paracrine

Progesterone prevents HGSOC by promoting precancerous cell pyroptosis via inducing fibroblast paracrine

Summary: High-grade serous ovarian carcinoma (HGSOC) is one of the most fatal gynecological cancers and has no effective prevention strategies. Herein, we demonstrated that progesterone significantly inhibited the occurrence, metastasis, and ascites of ovarian cancer in vivo, and the tumor inhibitio...

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Bibliographic Details
Main Authors: Nayiyuan Wu, Xiaoye Zhang, Zhibin Wang, Xiu Zhang, Chao Fang, He Li, Miaochen Zhu, Ying Wang, Qianjin Liao, Tangyuan Chu, Jing Wang
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:iScience
Subjects:
Microenvironment
Drugs
Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223006004

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http://www.sciencedirect.com/science/article/pii/S2589004223006004

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