Comparative proteomic analysis of silica-induced pulmonary fibrosis in rats based on tandem mass tag (TMT) quantitation technology.

Silicosis is a systemic disease characterized by chronic persistent inflammation and incurable pulmonary fibrosis with the underlying molecular mechanisms to be fully elucidated. In this study, we employed tandem mass tag (TMT) based on quantitative proteomics technology to detect differentially exp...

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Bibliographic Details
Main Authors: Cunxiang Bo, Xiao Geng, Juan Zhang, Linlin Sai, Yu Zhang, Gongchang Yu, Zhenling Zhang, Kai Liu, Zhongjun Du, Cheng Peng, Qiang Jia, Hua Shao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0241310