QSAR and Pharmacophore Modeling of Nitrogen Heterocycles as Potent Human <i>N</i>-Myristoyltransferase (Hs-NMT) Inhibitors

<i>N</i>-myristoyltransferase (NMT) is an important eukaryotic monomeric enzyme which has emerged as an attractive target for developing a drug for cancer, leishmaniasis, ischemia-reperfusion injury, malaria, inflammation, etc. In the present work, statistically robust machine leaning mo...

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Bibliographic Details
Main Authors: Magdi E. A. Zaki, Sami A. Al-Hussain, Vijay H. Masand, Siddhartha Akasapu, Israa Lewaa
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/7/1834