Dynamic Interplay between Lower-Grade Glioma Instability and Brain Metaplasticity: Proposal of an Original Model to Guide the Therapeutic Strategy

The behavior of lower-grade glioma (LGG) is changing over time, spontaneously, and in reaction to treatments. First, due to genomic instability and clonal expansion, although LGG progresses slowly during the early period of the disease, its growth velocity will accelerate when this tumor will transf...

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Bibliographic Details
Main Author: Hugues Duffau
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/19/4759