Dynamic Interplay between Lower-Grade Glioma Instability and Brain Metaplasticity: Proposal of an Original Model to Guide the Therapeutic Strategy
The behavior of lower-grade glioma (LGG) is changing over time, spontaneously, and in reaction to treatments. First, due to genomic instability and clonal expansion, although LGG progresses slowly during the early period of the disease, its growth velocity will accelerate when this tumor will transf...
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Format: | Article |
Language: | English |
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MDPI AG
2021-09-01
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Series: | Cancers |
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Online Access: | https://www.mdpi.com/2072-6694/13/19/4759 |