Daratumumab in the Treatment of Light-Chain (AL) Amyloidosis

Systemic light-chain (AL) amyloidosis is caused by a small B cell, most commonly a plasma cell (PC), clone that produces toxic light chains (LC) that cause organ dysfunction and deposits in tissues. Due to the production of amyloidogenic, misfolded LC, AL PCs display peculiar biologic features. The...

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Detalhes bibliográficos
Principais autores: Giovanni Palladini, Paolo Milani, Fabio Malavasi, Giampaolo Merlini
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2021-03-01
coleção:Cells
Assuntos:
Acesso em linha:https://www.mdpi.com/2073-4409/10/3/545