Eukaryotic-driven directed evolution of Cas9 nucleases
Abstract Background Further advancement of genome editing highly depends on the development of tools with higher compatibility with eukaryotes. A multitude of described Cas9s have great potential but require optimization for genome editing purposes. Among these, the Cas9 from Campylobacter jejuni, C...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-03-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-024-03215-9 |