Elite suppressor-derived HIV-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics.

Elite suppressor-derived HIV-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics.

Elite suppressors (ES) are a rare subset of HIV-1-infected individuals who are able to maintain HIV-1 viral loads below the limit of detection by ultra-sensitive clinical assays in the absence of antiretroviral therapy. Mechanism(s) responsible for this elite control are poorly understood but likely...

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Bibliographic Details
Main Authors: Kara G Lassen, Michael A Lobritz, Justin R Bailey, Samantha Johnston, Sandra Nguyen, Benhur Lee, Tom Chou, Robert F Siliciano, Martin Markowitz, Eric J Arts
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2661022?pdf=render

Internet

http://europepmc.org/articles/PMC2661022?pdf=render

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