Astroglial Connexin 43 Deficiency Protects against LPS-Induced Neuroinflammation: A TSPO Brain µPET Study with [<sup>18</sup>F]FEPPA

Astroglial Connexin 43 Deficiency Protects against LPS-Induced Neuroinflammation: A TSPO Brain µPET Study with [<sup>18</sup>F]FEPPA

Astroglial connexin 43 (Cx43) has been recognized as a crucial immunoregulating factor in the brain. Its inactivation leads to a continuous immune recruitment, cytokine expression modification and a specific humoral autoimmune response against the astrocytic extracellular matrix but without brain le...

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Bibliographic Details
Main Authors: Nicolas Vignal, Anne-Cécile Boulay, Carine San, Martine Cohen-Salmon, Nathalie Rizzo-Padoin, Laure Sarda-Mantel, Xavier Declèves, Salvatore Cisternino, Benoît Hosten
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
[<sup>18</sup>f]feppa
astrocytes
autoimmunity
blood–brain barrier
brain inflammation
connexin 43
pet imaging
tspo
Online Access:https://www.mdpi.com/2073-4409/9/2/389

Internet

https://www.mdpi.com/2073-4409/9/2/389

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