Linking erythropoietin to Treg-dependent allograft survival through myeloid cells

Linking erythropoietin to Treg-dependent allograft survival through myeloid cells

Erythropoietin (EPO) has multiple nonerythropoietic functions, including immune modulation, but EPO’s effects in transplantation remain incompletely understood. We tested the mechanisms linking EPO administration to prolongation of murine heterotopic heart transplantation using WT and conditional EP...

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Bibliographic Details
Main Authors: Julian K. Horwitz, Sofia Bin, Robert L. Fairchild, Karen S. Keslar, Zhengzi Yi, Weijia Zhang, Vasile I. Pavlov, Yansui Li, Joren C. Madsen, Paolo Cravedi, Peter S. Heeger
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-05-01
Series:JCI Insight
Subjects:
Transplantation
Online Access:https://doi.org/10.1172/jci.insight.158856

Internet

https://doi.org/10.1172/jci.insight.158856

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