Juvenile idiopathic arthritis with systemic onset with inflammatory bone lesions: two case reports of patients successfully treated with canakinumab and experience gained from literature

Non-bacterial osteomyelitis (NBO) is a rare chronic inflammatory bone disease related to immune system dysregulation. This disease belongs to a family of autoinflammatory diseases. It often coexists with other TNF-α-mediated immune-mediated diseases such as juvenile idiopathic arthritis (JIA) and in...

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Main Authors: Ekaterina I. Alexeeva, Tatyana M. Dvoryakovskaya, Irina T. Tsulukiya, Natalia M. Kondrateva, Natalia M. Solomatina, Gleb V. Kondratiev, Luliia V. Peshekhonova, Mikhail M. Kostik
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1163483/full