Study of Hydroxypropyl β-Cyclodextrin and Puerarin Inclusion Complexes Encapsulated in Sodium Alginate-Grafted 2-Acrylamido-2-Methyl-1-Propane Sulfonic Acid Hydrogels for Oral Controlled Drug Delivery

Puerarin has been reported to have anti-inflammatory, antioxidant, immunity enhancement, neuroprotective, cardioprotective, antitumor, and antimicrobial effects. However, due to its poor pharmacokinetic profile (low oral bioavailability, rapid systemic clearance, and short half-life) and physicochem...

Full description

Bibliographic Details
Main Authors: Abid Naeem, Chengqun Yu, Weifeng Zhu, Zhenzhong Zang, Yongmei Guan
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Gels
Subjects:
Online Access:https://www.mdpi.com/2310-2861/9/3/246