Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio

Collaboration among the multitude of RNA-binding proteins (RBPs) is ubiquitous, yet our understanding of these key regulatory complexes has been limited to single RBPs. We investigated combinatorial translational regulation by Drosophila Pumilio (Pum) and Nanos (Nos), which control development, fert...

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Bibliographic Details
Main Authors: Chase A Weidmann, Chen Qiu, René M Arvola, Tzu-Fang Lou, Jordan Killingsworth, Zachary T Campbell, Traci M Tanaka Hall, Aaron C Goldstrohm
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/17096