Single-Molecule Structure and Topology of Kinetoplast DNA Networks

Kinetoplast DNA (kDNA) is a two-dimensional Olympic-ring-like network of mutually linked DNA minicircles found in certain parasites called trypanosomes. Understanding the self-assembly and replication of this structure are not only major open questions in biology but can also inform the design of sy...

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Bibliographic Details
Main Authors: Pinyao He, Allard J. Katan, Luca Tubiana, Cees Dekker, Davide Michieletto
Format: Article
Language:English
Published: American Physical Society 2023-04-01
Series:Physical Review X
Online Access:http://doi.org/10.1103/PhysRevX.13.021010