Single-Molecule Structure and Topology of Kinetoplast DNA Networks
Kinetoplast DNA (kDNA) is a two-dimensional Olympic-ring-like network of mutually linked DNA minicircles found in certain parasites called trypanosomes. Understanding the self-assembly and replication of this structure are not only major open questions in biology but can also inform the design of sy...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
American Physical Society
2023-04-01
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Series: | Physical Review X |
Online Access: | http://doi.org/10.1103/PhysRevX.13.021010 |