CAXII inhibitors: Potential sensitizers for immune checkpoint inhibitors in HCC treatment

CAXII inhibitors: Potential sensitizers for immune checkpoint inhibitors in HCC treatment

Hepatocellular carcinoma (HCC) is a lethal malignancy with a lack of effective treatments particularly for the disease at an advanced stage. Even though immune checkpoint inhibitors (ICIs) have made great progress in the treatment of HCC, durable and ideal clinical benefits still cannot be achieved...

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Bibliographic Details
Main Authors: Rui Han, Jiayin Li, Jing Hony, Zhiwei Xiao, Jinghui wang, Man Yao, Shufang Liang, Lingeng Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
CAXII inhibition
sensitizer
antitumor immunity
ICIs based therapy
hepatocellular carcinoma
Tiliroside
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1052657/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1052657/full

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