Decosus: An R Framework for Universal Integration of Cell Proportion Estimation Methods

The assessment of the cellular heterogeneity and abundance in bulk tissue samples is essential for characterising cellular and organismal states. Computational approaches to estimate cellular abundance from bulk RNA-Seq datasets have variable performances, often requiring benchmarking matrices to se...

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Bibliographic Details
Main Authors: Chinedu A. Anene, Emma Taggart, Catherine A. Harwood, Daniel J. Pennington, Jun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.802838/full