Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem CellsSummary

Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem CellsSummary

Background & Aims: Self-renewal and multipotent differentiation are cardinal properties of intestinal stem cells (ISCs), mediated in part by WNT and NOTCH signaling. Although these pathways are well characterized, the molecular mechanisms that control the ‘stemness’ of ISCs are still not well de...

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Bibliographic Details
Main Authors: Chang-Kyung Kim, Madhurima Saxena, Kasmika Maharjan, Jane J. Song, Kenneth R. Shroyer, Agnieszka B. Bialkowska, Ramesh A. Shivdasani, Vincent W. Yang
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Intestinal Stem Cell
Multipotent Differentiation
Tissue Regeneration
Epigenetic Regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X1930164X

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http://www.sciencedirect.com/science/article/pii/S2352345X1930164X

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