Crosstalk among m6A RNA methylation, hypoxia and metabolic reprogramming in TME: from immunosuppressive microenvironment to clinical application

Crosstalk among m6A RNA methylation, hypoxia and metabolic reprogramming in TME: from immunosuppressive microenvironment to clinical application

Abstract The tumor microenvironment (TME), which is regulated by intrinsic oncogenic mechanisms and epigenetic modifications, has become a research hotspot in recent years. Characteristic features of TME include hypoxia, metabolic dysregulation, and immunosuppression. One of the most common RNA modi...

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Bibliographic Details
Main Authors: Fusheng Zhang, Haiyang Liu, Meiqi Duan, Guang Wang, Zhenghou Zhang, Yutian Wang, Yiping Qian, Zhi Yang, Xiaofeng Jiang
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Journal of Hematology & Oncology
Subjects:
Hypoxia
Tumor metabolism
Exosomes
Immune escape
Tumor biological functions
Tumor combination therapy
Online Access:https://doi.org/10.1186/s13045-022-01304-5

Internet

https://doi.org/10.1186/s13045-022-01304-5

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