The role of WDR5 in silencing human fetal globin gene expression

The role of WDR5 in silencing human fetal globin gene expression

Background Histone H3 lysine 4 (K4) methylation has been linked with transcriptional activity in mammalian cells. The WD40-repeat protein, WDR5, is an essential component of the MLL complex that induces histone H3 K4 methylation, but the role of WDR5 in human globin gene regulation has not yet been...

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Bibliographic Details
Main Authors: Zhen Xu, Yinghong He, Junyi Ju, Gerhard Rank, Loretta Cerruti, Chi Ma, Richard J. Simpson, Robert L. Moritz, Stephen M. Jane, Quan Zhao
Format: Article
Language:English
Published: Ferrata Storti Foundation 2012-11-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/6460

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https://haematologica.org/article/view/6460

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