Pulsatilla saponin D regulates ras-related C3 botulinum toxin substrate 3 (RAC3) to overcome resistance to paclitaxel in lung adenocarcinoma cells

Pulsatilla saponin D regulates ras-related C3 botulinum toxin substrate 3 (RAC3) to overcome resistance to paclitaxel in lung adenocarcinoma cells

Abstract Background Paclitaxel, a tubulin-binding agent, is a Food and Drug Administration-approved first-line drug for the treatment of non-small cell lung cancer (NSCLC), for both squamous and non-squamous cell lung carcinoma, with paclitaxel/carboplatin + bevacizumab a common chemotherapy regimen...

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Bibliographic Details
Main Authors: Yanyan Lu, Wubin He, Xiaoxu Huang, Xuyang Xiao
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Cancer
Subjects:
Pulsatilla saponin D
RAC3
Paclitaxel
Resistance
Lung adenocarcinoma cell
Online Access:https://doi.org/10.1186/s12885-024-11841-6

Internet

https://doi.org/10.1186/s12885-024-11841-6

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