A new anabolic compound, LLP2A-Ale, reserves periodontal bone loss in mice through augmentation of bone formation

Abstract Background Currently, there are no effective medications to reverse periodontal disease (PD)-induced bone loss. The objective of this study was to test a new anabolic compound, LLP2A-Ale, or with the combination treatment of mesenchymal stromal cell (MSC), in the treatment of bone loss seco...

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Bibliographic Details
Main Authors: Min Jiang, Lixian Liu, Ruiwu Liu, Kit S. Lam, Nancy E. Lane, Wei Yao
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Pharmacology and Toxicology
Online Access:http://link.springer.com/article/10.1186/s40360-020-00454-x