A Rabbit Model for the Evaluation of Drugs for Treating the Chronic Phase of Botulism

Antitoxin, the only licensed drug therapy for botulism, neutralizes circulating botulinum neurotoxin (BoNT). However, antitoxin is no longer effective when a critical amount of BoNT has already entered its target nerve cells. The outcome is a chronic phase of botulism that is characterized by prolon...

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Bibliographic Details
Main Authors: Amram Torgeman, Eran Diamant, Eyal Dor, Arieh Schwartz, Tzadok Baruchi, Alon Ben David, Ran Zichel
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/13/10/679